Professor Worthley has authored more than 250 peer-reviewed publications spanning the spectrum of cardiovascular medicine — from high-resolution cardiac imaging with MRI and CT to the development and evaluation of novel coronary interventional devices, transcatheter aortic valve implantation (TAVI) platforms, and emerging mitral valve therapies. The following are some interviews and presentations and five of his most influential and clinically significant papers from recent years.

Publications and Presentations

  1. First-in-Human Evaluation of a Novel Polymer-Free Drug-Filled Stent: Angiographic, IVUS, OCT, and Clinical Outcomes From the RevElution Study
    Worthley SG, Abizaid A, Kirtane AJ, Simon DI, Meredith IT, Sinnaeve PR, et al
    JACC: Cardiovascular Interventions. 2017;10(2):147-156. doi:10.1016/j.jcin.2016.10.020

  2. Transcatheter reshaping of the mitral annulus in patients with functional mitral regurgitation: one-year outcomes of the MAVERIC trial.
    Worthley S,     Redwood S, Hildick-Smith D, Rafter T, Whelan A, De Marco F, Horrigan M, Delacroix S, Gregson J, Erglis A.
    EuroIntervention. 2021;16(13):1106-1113. doi:10.4244/EIJ-D-20-00484.

  3. 1-Year Outcomes Following Transfemoral Transseptal Transcatheter Mitral Valve Replacement: The HighLife TSMVR Feasibility Study
    Schneider LM, Worthley S, Nickenig G, Huczek Z, Wojakowski W, Tchetche D, Dubois C, Nasr M, Verhees L, Rothman M, Piazza N, Buithieu J, Yeow WL, Kessler M, Rottbauer W.
    JACC: Cardiovascular Interventions. 2023;16(23):2854-2865. doi:10.1016/j.jcin.2023.09.003.

  4. Thirty-day and one-year outcomes of the Navitor transcatheter heart valve in patients with aortic stenosis: the prospective, multicentre, global PORTICO NG Study.
    Søndergaard L, Walton AS, Worthley SG, Smith D, Chehab B, Manoharan G, Yong G, Bedogni F, Bates N, Reardon MJ.
    EuroIntervention. 2023;19(3):248-255. doi:10.4244/EIJ-D-22-01108.

  5. Thirty-Day and 1-Year Outcomes of Navitor Transcatheter Aortic Valve in Low- or Intermediate-Risk Patients.
    Worthley SG    , Giordano A, Corcione N, Nombela-Franco L, De Marco F, Walton A, Bedogni F, Möllmann H, De Backer O, Leroux L, Manoharan G, Tchétché D, Taramasso M, Li L, Kuo H-C, Van Mieghem NM; VANTAGE study investigators
    JACC: Cardiovascular Interventions. 2025; Epub ahead of print (Aug 21, 2025). doi:10.1016/j.jcin.2025.08.021.